Operation Smile is a private, not-for-profit volunteer medical services organization providing reconstructive surgery and related health care to indigent children and young adults in developing countries and the United States. Operation Smile provides education and training around the world to physicians and other health care professionals to achieve long-term self-sufficiency.
http://www.operationsmile.org/
One of the greatest of the charitable relief organisations in my opinion. My association with TEAR goes back more than 20 years. Their overheads are low. They work hand-in-hand with local churches in developing communities. They get the job done.
http://www.tear.org.au/
The Annual Internet Toy Drive in support of the official Marines Toys for Tots Program makes it as easy as a few clicks for you to help a needy child this Christmas.
http://www.internettoydrive.org/
The Hunger Site focuses the power of the Internet on a specific humanitarian need; the eradication of world hunger.
http://www.thehungersite.com/
World Vision aims to share and demonstrate the love and compassion that Jesus extended to all people - especially to those suffering from poverty, oppression or injustice. It's the biggest relief agency by far in this country and they do magnificent work. They have their critics, but I've seen some of their work first hand. Truly wonderful!
http://www.worldvision.com.au/